one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity connected with bortezomib, a proteasome inhibitor Utilized in the procedure of multiple myeloma. Its synthesis or analyze is important for guaranteeing the purity and safety from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug Utilized in the remedy of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-ten-one): A important compound in the synthesis of imatinib, a drug that targets distinct sorts of cancer, such as Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their study is significant for optimizing the creation procedure and guaranteeing large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is made use of to deal with breast cancer, and these intermediates are involved with its generation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Employed in the therapy of breast cancer. Many intermediates help in the synthesis of this drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): CAS NO. 114611-53-9 This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug effective in dealing with cancers such as ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the cure of colorectal most cancers and modest mobile lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved with the synthesis of adamantane derivatives, that have many purposes, such as antiviral Homes.
Vildagliptin Intermediates: Utilized in the creation of vildagliptin, an oral drug for kind 2 diabetes that inhibits the enzyme DPP-four to manage blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS 3-(4-Nitro-1-oxo-1 NO. 61259-forty eight-one): This compound is associated with the synthesis of varied gluconic acid derivatives, which might be Utilized in foodstuff, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication utilised to handle sort 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).